李艳芳 副教授/硕导

学科（专业）：神经生物学

研究方向：神经系统疾病的分子机制研究        

邮   箱：yfli@xmu.edu.cn

电   话：0592-2880582

代表性论文:

1. Rong Z, Cheng B, Zhong L, Ye X, Li X, Jia L, Li Y, Shue F, Wang N, Cheng Y, Huang X, Liu CC, Fryer JD, Wang X, Zhang YW, Zheng H (2020). Activation of FAK/Rac1/Cdc42-GTPase signaling ameliorates impaired microglial migration response to Abeta(42) in triggering receptor expressed on myeloid cells 2 loss-of-function murine models.FASEB J. Online ahead of print.

2. Miralles CP, Taylor MJ, Bear J Jr, Fekete CD, George S, Li Y, Bonhomme B, Chiou TT, De Blas AL (2020) Expression of protocadherin-gammaC4 protein in the rat brain.J Comp Neurol. 528:840-864.

3. Pan G, Chen Z, Zheng H, Zhang Y, Xu H, Bu G, Zheng H, Li Y* (2018). Compensatory mechanisms modulate the neuronal excitability in a kainicacid-induced epilepsy mouse model. Frontiers in Neural Circuits. 12: 48.

4. Ye X, Rong Z, Li Y, Wang X, Cheng B, Cheng Y, Luo H, Ti Y, Huang X, Liu Z, Zhang YW, Zheng W, Zheng H* (2018). Protective role of L-3-n-butylphthalide in cognitive function and dysthymic disorders in mouse with chronic epilepsy. Frontiers in Pharmacology. 9: 734.

5. Zhao D, Meng J, Zhao Y, Huo Y, Liu Y, Zheng N, Zhang M, Gao Y, Chen Z, Sun H, Wang X, Jing C, Zhang T, Zhang X, Luo H, Wang X, Zhang J, Liu FR, Li Y, Bu G, Wen L, Huang TY, Xu H, Zhang YW* (2018). RPS23RG1 is required for synaptic integrity and rescues Alzheimer's disease-associated cognitive deficits.  Biological Psychiatry. Epub ahead of print

6. Li Y*, Chen Z, Gao Y, Pan G, Zheng H, Zhang YW, Xu H, Bu G, Zheng H*. (2017) Synaptic adhesion molecule Pcdh-γC5 mediates synaptic dysfunction in Alzheimer's disease. Journal of Neuroscience.37: 9259-9268.

7. Li Y*, Sun H, Chen Z, Xu H, Bu G, Zheng H*. (2016) Implications of GABAergic neurotransmission in Alzheimer's disease. Frontiers in Aging Neuroscience. 8:31.

8. Wang F, Zheng H, Zhang X, Li Y,Gao Z, Wang Y, Liu X, Yao Y*. (2016) Successful surgery in lesional epilepsy secondary to posterior quandrant ulegyria coexisting with benign childhood focal epilepsy: A case report. Clinical Neurology and Neurosurgery.149:94-97.

9. Zhang X, Li Y, Xu H, Zhang YW*. (2014) The γ-secretase complex: from structure to function. Frontiers in Cellular Neuroscience. 8:427.

10. Jiang S, Li Y^#, Zhang C, Zhao Y, Bu G, Xu H, Zhang YW*. (2014) M1 muscarinic acetylcholine receptor in Alzheimer’s disease. Neuroscience Bulletin.30: 295-307.

11. Jiang S, Li Y^#, Zhang X, Bu G, Xu H, Zhang YW*. (2014) Trafficking regulation of proteins in Alzheimer's disease. Molecular Neurodegeneration. 9:6.

12. Li Y, Xiao H, Chiou TT, Jin H, Bonhomme B, Miralles CP, Pinal N, Ali R, Chen WV, Maniatis T, De Blas AL*. (2012) Molecular and functional interaction between protocadherin-γC5 and GABA_A receptors. Journal of Neuroscience.32:11780-117897.

13. Li Y, Serwanski DR, Miralles CP, Fiondella CG, Loturco JJ, Rubio ME, De Blas AL*. (2010) Synaptic and non-synaptic localization of protocadherin-γC5 in the rat brain, Journal of Comparative Neurology. 518: 3439-5463.

14. Li Y, Wu LJ, Li Y, Xu L, Xu TL*. (2003) Mechanisms of H⁺ modulation of glycine response in rat sacral dorsal commissural neurons. Journal of Physiology. 552:73-87.

15. Li Y, Li Y, Xu TL*. (2003) Inhibition of glycine response by amiloride in rat spinal neurons. Neuroscience Letters. 345:173-176.

16. Li Y, Li Y, Xu TL*. (2003) Amiloride inhibition of glycinergic miniature IPSCs in mechanically dissociated rat spinal neurons. Neuroscience Letters.349:17-20.